The spirochete T. pallidum causes syphilis. Other spirochetes cause Lymes disease, yaws, bejel. The relationship between a past history of syphilis and AIDS is highly controversial. (Sometime I will post the key links about this debate.) The most startling information I've run into in a long time has to do with possible links between spirochetes and Alzheimers and spirochetes and Multiple Sclerosis. Judit Miklossy, in an article in NeuroReport in 1993, confirmed that in autopsies of 14 cases of confirmed Alzheimers Disease, spirochetes were found in the blood, spinal fluid, and brain tissue. No spirochetes were found in a control group. Now Colman Jones emails me another fascinating reference: a 2001 article in Infection showing spirochetal cysts in the spinal fluid of 10 out of 10 MS patients. Small samples, old research, but . . . did anyone follow up? Try to replicate it? It is certainly worth getting these articles and seeing where they led, if anywhere. Pertinent question: WHICH spirochetes did they find?
SPIROCHETES AND ALZHEIMER'S:
Complete article: "Alzheimer's disease--a spirochetosis?, Miklossy J,
Neuroreport 1993 Jul;4(7):841-8
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as of 23 September 1998
NeuroReport 4, §41-§48 (1993)
NeuroReport Vol. 4 No. 7 July 1993 [pages 841-848]
Alzheimer's disease--a spirochetosis?
Judit Miklossy
University Institute of Pathology, Division of Neuropathology,
University of Lausanne, Rue du Bugnon 27, 1005 Lausanne, Switzerland
The aetiology of Alzheimer's disease (AD), which affects a large
proportion of the aged population is unknown and the treatment
unresolved. The role of beta amyloid protein (ßA4), derived from a
larger amyloid precursor protein (APP) in AD is the subject of intense
research. Here I report observations that in 14 autopsy cases, with
histopathologically confirmed AD, spirochetes were found in blood and
cerebrospinal fluid and, moreover, could be isolated from brain tissue.
Thirteen age-matched control cases were without spirochetes. Reference
strains of spirochetes and those isolated from brains of AD patients,
showed positive immunoreaction with monoclonal antibody against the ß
amyloid precursor protein. These observations suggest that spirochetes
may be one of the causes of AD and that they may be the source of the ß
amyloid deposited in the AD brain.
SPIROCHETES AND MS
From Colman's email:
"An interesting historical note, which you may already be familiar with: In
the first half of the 20th century, MS was widely believed to be an
infectious disease, and there were suspicions that it might be a
spirochetal infection due to the waxing/waning nature of the symptoms. One
of the most fascinating papers on this is "Acute plaques in multiple
sclerosis, their pathogenic significance and the role of spirochaetes as
etiological factor." by Dr. Gabriel Steiner in the Journal of
Neuropathology, 11:343-72. 1952. If you can't get a copy, I have an
abbreviated PDF version I could email to you. It's particularly intriguing in
light of the 2001 paper by the Brorsons in Norway ("Association between
multiple sclerosis and cystic structures in cerebrospinal fluid." Brorson
O, Brorson SH, Henriksen TH, Skogen PR, Schoyen R. Infection. 2001
Dec;29(6):315-9), which found spirochetal cysts in the spinal fluid of 10
out of 10 MS patients."
please send me a copy of your PDF file on Sprochetes and MS
Thanks,
Joseph Labrum
Posted by: Joseph Labrum | October 03, 2003 at 08:15 AM
Is the next step as simple as a bunch of us with MS getting tested for spirochates before we are stiffs?
Posted by: bill dodd | October 12, 2003 at 06:29 PM
I wonder if you or any of your readers have come across convincing evidence that Meriwether Lewis and several members of his expedition have contracted syphilis and ultimately succumbed to the debilitating effects of paresis?
Why did you not include his story or that of Randolph Churchill
in your book?
Posted by: Frank Georg | October 20, 2003 at 02:37 PM
Yes: a good case has been made for Meriwether Lewis. I have just read a manuscript-in-the-works by Tom Lowry that brings together the information about Lewis with what was known about syphilis at that time in the West. I mentioned Lewis in the chapter "Pox Gallery" as a suspected syphilitic
See the Ravenholt and Ambrose correspondence about syphilis:
http://hnn.us/articles/printfriendly/666.html
I included a longer section in that chapter about Randolph Churchill, who was one of the few paretics whose disease was publicly known during his lifetime. What did Winston know, think, feel about his father's disease? You can read many biographies of Winston that fail to mention Randolph illness, though there is good information that it was well-known to him. On his last trip to Europe, Randolph had a shopping compulsion typical of incipient paresis. His wife Jenny followed him around returning the items that he bought. Fearing death on the trip, they traveled accompanied by a lead coffin. This from a book about Jenny.
Posted by: Deb Hayden | October 20, 2003 at 08:54 PM
Could you please send me a copy of MS and spirochetes? thanks shawna
Posted by: shawna penna | November 24, 2003 at 08:21 PM
Hi my name is Tammy . Iwas diagnosed with secondary progressive ms then primary progressive ms and treated for it for 91/2 years only to find a llmd and find the reason for my ms symptoms was lyme. I have been off all ms medications and have made a great improvement. I have started school and can go for walks now. If anyone has any information on ms and lyme they would want to send me I would greatly appreciate it. I have helped many others who were told ms only to learn the reasons behind there symptoms was the spirochete. My e-mail is talyn 2620@aol.com Thanks Tammy
Posted by: Tammy | February 11, 2004 at 08:38 PM
please send me a copy of your PDF file on Sprochetes and MS
Thanks,
Lizie
Posted by: lizzie | May 26, 2004 at 01:27 AM
please send me a copy of your PDF file on Sprochetes and MS
Thanks,
Lizzie
Posted by: lizzie | May 26, 2004 at 01:28 AM
Could you please send me a copy of your PDF file on Spirochetes and MS.
Thank you,
Lidia
Posted by: Lidia | February 13, 2005 at 06:29 PM
Could you please send me a copy of your PDF file on Spirochetes and MS. and Spirochetes and Alzhimers. thanks abha
Posted by: abha | January 20, 2006 at 06:58 AM